Schmitt Sabine, Paro Renato
Zentrum für Molekulare Biologie Heidelberg (ZMBH), University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
Genome Biol. 2006;7(5):218. doi: 10.1186/gb-2006-7-5-218. Epub 2006 May 26.
Expression of the genetic information encoded in our genomes is usually regulated by proteins interacting with the DNA. In some cases, however, noncoding RNAs transcribed from DNA control elements cooperate with histone-modifying enzymes to regulate gene expression, as has recently been shown for noncoding RNA originating from Polycomb- and Trithorax-group response elements.
我们基因组中编码的遗传信息的表达通常由与DNA相互作用的蛋白质来调控。然而，在某些情况下，从DNA调控元件转录而来的非编码RNA会与组蛋白修饰酶协同作用来调控基因表达，最近针对源自多梳蛋白和三胸蛋白反应元件的非编码RNA的研究就表明了这一点。
