Bratberg Grete H, Nilsen Tom I L, Holmen Turid L, Vatten Lars J
HUNT Research Centre, Faculty of Medicine, Norwegian University of Science and Technology, Verdal, Norway.
Eur J Pediatr. 2006 Nov;165(11):787-93. doi: 10.1007/s00431-006-0174-4. Epub 2006 May 30.
Shorter adult stature has been attributed to early sexual maturation, as well as early adiposity, but it is not clear if these factors are interrelated.
A number of 1,605 Norwegian adolescents were followed from early (baseline) to late adolescence (follow-up). Maturational timing was assessed by self-reports of pubertal status (pubertal development scale, PDS) in boys and age at menarche (AAM) in girls. Height, weight and waist circumference were measured at baseline and at follow-up. Differences in height at follow-up and height gain related to the timing of sexual maturation and the level of central adiposity (i.e. high or low waist circumference) at baseline were estimated using general linear modelling. At follow-up, the median height was 180 cm in boys and 167 cm in girls. Early maturing boys and girls with relatively high central adiposity at baseline were, on average, 5.7 cm (P value<0.001) and 3.6 cm (P value<0.001) taller than early maturing boys and girls with low central adiposity. Differences in stature related to central adiposity were less pronounced for intermediate and late maturing boys and girls. The height was lowest in boys (176.6 cm) and girls (163.8 cm) who had matured early and had low central adiposity at baseline. Height gain during follow-up was independent of the level of central adiposity, but was closely related to the timing of sexual maturation. The association between the early timing of sexual maturation and subsequent height was modified by the level of central adiposity in early adolescence.
The results suggest that early maturity combined with adiposity yields higher stature than early maturity and leanness.
成年人身材较矮被认为与性早熟以及过早肥胖有关，但尚不清楚这些因素之间是否相互关联。
对1605名挪威青少年从青春期早期（基线期）到晚期（随访期）进行了跟踪研究。性成熟时间通过男孩青春期状态的自我报告（青春期发育量表，PDS）以及女孩月经初潮年龄（AAM）来评估。在基线期和随访期测量身高、体重和腰围。使用一般线性模型估计随访期身高差异以及与性成熟时间和基线期中心性肥胖水平（即高或低腰围）相关的身高增长情况。随访时，男孩的中位身高为180厘米，女孩为167厘米。基线期中心性肥胖程度相对较高的早熟男孩和女孩，平均比中心性肥胖程度较低的早熟男孩和女孩高5.7厘米（P值<0.001）和3.6厘米（P值<0.001）。对于中度和晚熟的男孩和女孩，与中心性肥胖相关的身高差异不太明显。基线期早熟且中心性肥胖程度低的男孩（176.6厘米）和女孩（163.8厘米）身高最低。随访期间的身高增长与中心性肥胖水平无关，但与性成熟时间密切相关。青春期早期的性早熟与随后身高之间的关联受到青春期早期中心性肥胖水平的影响。
结果表明，早熟与肥胖相结合比早熟与消瘦产生更高的身材。
