铑催化下，通过逆烯丙基化反应，将高烯丙醇中的烯丙基转移至醛上，随后异构化为酮。
Rhodium-catalyzed allyl transfer from homoallyl alcohols to aldehydes via retro-allylation followed by isomerization into ketones.
作者信息
Takada Yuko, Hayashi Sayuri, Hirano Koji, Yorimitsu Hideki, Oshima Koichiro
机构信息
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
出版信息
Org Lett. 2006 Jun 8;8(12):2515-7. doi: 10.1021/ol060710v.
PMID:16737302
Abstract
Retro-allylation of homoallyl alcohol by rhodium catalysis occurs to generate allylrhodium species. This allylrhodium reacts with aldehydes to give the corresponding secondary alcohols in situ. Isomerization of these alcohols proceeds in the same pots to furnish the corresponding saturated ketones in good yields. [reaction: see text]
摘要
通过铑催化实现高烯丙醇的反烯丙基化反应，生成烯丙基铑物种。该烯丙基铑与醛反应，原位生成相应的仲醇。这些醇在同一反应釜中进行异构化反应，以良好的产率得到相应的饱和酮。[反应：见正文]
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