Lenzenweger Mark F
Department of Psychology, State University of New York at Binghamton, NY 13902, USA.
J Abnorm Psychol. 2006 May;115(2):195-200. doi: 10.1037/0021-843X.115.2.195.
Paul E. Meehl proposed a model of the cause and pathogenesis of schizophrenia and related states in the early 1960s (Meehl, 1962), which he later revised in 1990 (Meehl, 1990). His model emphasized a genetically influenced aberration in neural transmission that could eventuate in clinical schizophrenia, nonpsychotic schizotypic states, or apparent normalcy depending on the coexistence of other factors. His model embodied the core ideas of the diathesis-stressor framework that would come to dominate experimental and developmental psychopathology for the next 40 years. The author reviews Meehl's model of schizotaxia, schizotypy, and schizophrenia and reviews and clarifies some frequent misunderstandings of the model.
保罗·E·米尔在20世纪60年代初提出了一种精神分裂症及相关状态的病因和发病机制模型（米尔，1962年），他后来在1990年对该模型进行了修订（米尔，1990年）。他的模型强调了神经传递中受基因影响的异常，这种异常可能最终导致临床精神分裂症、非精神病性分裂型状态或看似正常的状态，这取决于其他因素的共存情况。他的模型体现了素质-应激框架的核心思想，该框架在接下来的40年里主导了实验性和发展性精神病理学领域。作者回顾了米尔关于分裂型人格、分裂型特质和精神分裂症的模型，并回顾和澄清了对该模型的一些常见误解。
