Frisvad Jens C, Larsen Thomas O, Dalsgaard Petur W, Seifert Keith A, Louis-Seize Gerry, Lyhne E K, Jarvis Bruce B, Fettinger James C, Overy David P
Center for Microbial Biotechnology, BioCentrum-DTU, Building 221, Søltofts Plads, DK-2800 Kgs, Lyngby, Denmark.
Biodiversity (Mycology and Botany), National Programme on Environmental Science, Agriculture and Agri-Food Canada, Ottawa, Ontario K1A 0C6, Canada.
Int J Syst Evol Microbiol. 2006 Jun;56(Pt 6):1427-1437. doi: 10.1099/ijs.0.64160-0.
Penicillium jamesonlandense is a novel species from Greenland that grows exceptionally slowly at 25 degrees C and has an optimum temperature for growth of 17-18 degrees C. The novel species is more psychrotolerant than any other Penicillium species described to date. Isolates of this novel species produce a range of secondary metabolites with a high chemical diversity, represented by kojic acid, penicillic acid, griseofulvin, pseurotin, chrysogine, tryptoquivalins and cycloaspeptide. Penicillium ribium, another novel psychrotolerant species from the Rocky Mountains, Wyoming, USA, produces asperfuran, kojic acid and cycloaspeptide. Originally reported from an unidentified Aspergillus species isolated from Nepal, cycloaspeptide A is reported here for the first time from the two novel Penicillium species and two known psychrotolerant species with high chemical diversity, Penicillium soppii and Penicillium lanosum. All species, except P. ribium, produce a combination of cycloaspeptide and griseofulvin. However, P. ribium (3/5 strains) produced the precursor to griseofulvin, norlichexanthone. The type strain of Penicillium jamesonlandense sp. nov. is DAOM 234087(T) (=IBT 21984(T) = IBT 24411(T) = CBS 102888(T)) and the type strain of Penicillium ribium sp. nov. is DAOM 234091(T) (=IBT 16537(T) = IBT 24431(T)).
詹姆逊青霉是一种来自格陵兰岛的新物种，在25摄氏度时生长异常缓慢，最适生长温度为17 - 18摄氏度。该新物种比迄今描述的任何其他青霉物种更耐低温。这种新物种的分离株产生一系列具有高化学多样性的次生代谢产物，以 kojic 酸、penicillic 酸、灰黄霉素、pseurotin、chrysogine、色氨酸等价物和环肽为代表。来自美国怀俄明州落基山脉的另一种新的耐低温物种——里氏青霉，产生asperfuran、kojic 酸和环肽。环肽A最初报道于从尼泊尔分离出的一种未鉴定的曲霉属物种，本文首次报道从这两种新的青霉物种以及两种已知的具有高化学多样性的耐低温物种——索氏青霉和羊毛状青霉中分离得到环肽A。除里氏青霉外，所有物种都产生环肽和灰黄霉素的组合。然而，里氏青霉（3/5菌株）产生了灰黄霉素的前体——降红藓酮。詹姆逊青霉新种的模式菌株是DAOM 234087(T)（=IBT 21984(T) = IBT 24411(T) = CBS 102888(T)），里氏青霉新种的模式菌株是DAOM 234091(T)（=IBT 16537(T) = IBT 24431(T)）。
