Contreras-Soto J, Forsbach G, Vazquez-Rosales J, Alvarez-Garcia C, Garcia G
Hospital de Gineco-Obstetricia Dr. I. Morones, IMSS, Monterrey, N.L., Mexico.
Int J Gynaecol Obstet. 1991 Mar;34(3):205-10. doi: 10.1016/0020-7292(91)90350-e.
We analyzed 215 consecutive patients with diabetes mellitus and pregnancy, 118 (54.83%) with noninsulin dependent diabetes mellitus (NIDDM), 90 (41.86%) with gestational diabetes mellitus (GDM) and 7 (3.26%) with insulin dependent diabetes mellitus (IDDM). NIDDM and GDM patients had no significant difference in age and body mass index. There were no maternal deaths, nor episodes of ketoacidosis. Maternal and neonatal complications occurred with a similar frequency in NIDDM and GDM. We concluded that in our population, diabetes associated with insulin-resistance occurred in over 96% of our pregnant diabetic patients and was associated with an increased prevalence of maternal and neonatal complications. Earlier perinatal care has to be established in NIDDM patients, and obese young women should be screened to detect GDM from early gestation and advised to reduce weight before pregnancy ensues.
我们分析了215例连续的糖尿病合并妊娠患者，其中118例（54.83%）为非胰岛素依赖型糖尿病（NIDDM），90例（41.86%）为妊娠期糖尿病（GDM），7例（3.26%）为胰岛素依赖型糖尿病（IDDM）。NIDDM和GDM患者在年龄和体重指数方面无显著差异。无孕产妇死亡病例，也无酮症酸中毒发作。NIDDM和GDM患者发生母婴并发症的频率相似。我们得出结论，在我们的研究人群中，超过96%的妊娠糖尿病患者患有与胰岛素抵抗相关的糖尿病，且与母婴并发症患病率增加有关。必须为NIDDM患者建立更早的围产期护理，对于肥胖的年轻女性，应进行筛查以在妊娠早期检测出GDM，并建议她们在怀孕前减轻体重。
