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爱丁堡吸毒者中的艾滋病:对该流行病的观察及其未来管理的启示。

AIDS in Edinburgh drug users: observations on the epidemic and implications for its future management.

作者信息

Flegg P J, Brettle R P

机构信息

Regional Infectious Diseases Unit, City Hospital, Edinburgh, Scotland, U.K.

出版信息

J Infect. 1991 Mar;22(2):113-8. doi: 10.1016/0163-4453(91)91459-b.

DOI:10.1016/0163-4453(91)91459-b
PMID:1673989
Abstract

We are now witnessing the anticipated explosion of cases of AIDS resulting from the epidemic of HIV infection among Edinburgh drug users in the first half of the last decade. We expect the number of new cases of AIDS to continue to increase, although the rate at which they do so may be mitigated by intervention which slows the rate of progression to AIDS. There is evidence that current management of patients may postpone a diagnosis of AIDS until later in the natural history of HIV infection when immunity is very low as manifested by CD4+ lymphocyte counts. Health care planners need to provide resources for an increasing number of HIV-infected persons who have not yet fulfilled the definition of AIDS but who nevertheless require extensive resources both in the community and in hospital.

摘要

我们正在见证预期中艾滋病病例的激增,这是由上世纪九十年代上半年爱丁堡吸毒者中艾滋病毒感染流行所导致的。我们预计艾滋病新病例数量将持续增加,尽管通过减缓向艾滋病发展速度的干预措施,其增长速度可能会得到缓解。有证据表明,目前对患者的管理可能会将艾滋病诊断推迟到艾滋病毒感染自然史的后期,此时免疫力很低,表现为CD4 +淋巴细胞计数。卫生保健规划者需要为越来越多尚未符合艾滋病定义但在社区和医院仍需要大量资源的艾滋病毒感染者提供资源。

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Br J Clin Pharmacol. 1993 Oct;36(4):293-301. doi: 10.1111/j.1365-2125.1993.tb00367.x.