Deleu Dirk, Hamad Ayman A, Kamram Saadat, El Siddig Abbas, Al Hail Hassan, Hamdy Samir M K
Department of Neurology, Hamad Medical Corporation, Doha, State of Qatar.
Arch Med Res. 2006 Jul;37(5):655-62. doi: 10.1016/j.arcmed.2006.01.001.
Ischemic stroke is influenced by ethnic and geographical variations. The aim of this study was to identify the risk factor profiles, subtypes and recurrence of non-cardioembolic ischemic stroke for the two largest subpopulations, the Arab and South Asians, at the only stroke-admitting hospital in Qatar.
Data on stroke patients admitted to Hamad Medical Corporation from January through December 2001 were reviewed in January 2005. Only patients with non-cardioembolic ischemic stroke and complete work-up were included.
A total of 303 patients with ischemic non-cardioembolic stroke fit the entry criteria. Sixty seven percent of the overall patient population (sex ratio 2:6, M/F) was of Arab origin, and 32% were South Asians. Hypertension was the most commonly encountered risk factor followed by dyslipidemia, diabetes mellitus, and obesity. Significant differences between the Arab and South Asian subgroup of patients were observed with respect to number of risk factors and occurrence of obesity and diabetes. Carotid artery stenotic lesions, ventricular wall motion abnormalities and stroke recurrence were observed with a higher frequency in the Arab subgroup of patients compared with the South Asians. The majority of strokes were lacunar hemispheric strokes (68%), followed by lacunar brainstem strokes (15%) and large-vessel hemispheric infarctions (10%). Patients with a previous history of stroke had a higher frequency of carotid artery stenosis (p = 0.05) and risk of stroke recurrence (p = 0.04).
Unlike in other studies originating from the Arabian Gulf, lacunar stroke is the most common subtype of non-cardioembolic ischemic stroke in both the Arabs and South Asians in Qatar. Significant ethnic differences in age of occurrence, risk factor profile, and cardiovascular variables were observed.
缺血性中风受种族和地域差异的影响。本研究的目的是在卡塔尔唯一一家收治中风患者的医院，确定阿拉伯和南亚这两个最大亚人群中非心源性缺血性中风的危险因素概况、亚型及复发情况。
2005年1月回顾了2001年1月至12月期间哈马德医疗公司收治的中风患者数据。仅纳入非心源性缺血性中风且检查完整的患者。
共有303例非心源性缺血性中风患者符合纳入标准。总体患者人群的67%（男女比例为2:6）为阿拉伯裔，32%为南亚裔。高血压是最常见的危险因素，其次是血脂异常、糖尿病和肥胖。在危险因素数量以及肥胖和糖尿病的发生率方面，阿拉伯和南亚患者亚组之间存在显著差异。与南亚患者相比，阿拉伯患者亚组中颈动脉狭窄病变、心室壁运动异常和中风复发的发生率更高。大多数中风为腔隙性半球中风（68%），其次是腔隙性脑干中风（15%）和大血管半球梗死（10%）。有中风既往史的患者颈动脉狭窄发生率更高（p = 0.05），中风复发风险更高（p = 0.04）。
与源自阿拉伯湾的其他研究不同，在卡塔尔的阿拉伯人和南亚人中，腔隙性中风是非心源性缺血性中风最常见的亚型。在发病年龄、危险因素概况和心血管变量方面观察到显著的种族差异。
