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摄入3%过氧化氢后出现出血性胃炎和气栓

Hemorrhagic gastritis and gas emboli after ingesting 3% hydrogen peroxide.

作者信息

Moon Jeong Mi, Chun Byeong Jo, Min Yong Il

机构信息

Department of Emergency Medicine, Chonnam National University Hwasun Hospital and Chonnam Medical School, Gwangju, South Korea.

出版信息

J Emerg Med. 2006 May;30(4):403-6. doi: 10.1016/j.jemermed.2005.05.036.

DOI:10.1016/j.jemermed.2005.05.036
PMID:16740449
Abstract

It is well known that ingestion of low concentrations of hydrogen peroxide is usually nontoxic; this does not produce gas embolism and is only a mild irritant to the gastrointestinal tract. We report the case of a 25-year-old woman who ingested one mouthful of 3% hydrogen peroxide and presented to the Emergency Department with persistent vomiting and epigastric pain. The radiographic evaluation found portal venous gas emboli. In addition, upper gastrointestinal endoscopy performed 2 h after ingestion revealed diffuse hemorrhagic gastritis. She showed a decrease of hemoglobin concentration and a positive test result for occult blood in stool. She was observed for 14 days and discharged. Follow-up endoscopy showed erythematous gastritis. This case illustrates that a low concentration of hydrogen peroxide can cause portal venous gas embolism and severe gastrointestinal injuries even if only a small amount is ingested.

摘要

众所周知,摄入低浓度过氧化氢通常无毒;它不会产生气体栓塞,只是对胃肠道有轻度刺激。我们报告一例25岁女性病例,她摄入一口3%的过氧化氢后前往急诊科,出现持续呕吐和上腹部疼痛。影像学评估发现门静脉气体栓塞。此外,摄入后2小时进行的上消化道内镜检查显示弥漫性出血性胃炎。她血红蛋白浓度降低,粪便潜血试验呈阳性。对她进行了14天的观察后出院。随访内镜检查显示为红斑性胃炎。该病例表明,即使仅摄入少量低浓度过氧化氢也可导致门静脉气体栓塞和严重的胃肠道损伤。

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