Dominguez Dominique, Walton Rebecca
VCA West Los Angeles Animal Hospital, 1900 S. Sepulveda Boulevard, Los Angeles, California 90025, USA (Dominguez, Walton); Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, 1800 Christensen Drive, Ames, Iowa 50011, USA (Walton).
Can Vet J. 2025 Jun;66(6):617-621.
An 8-month-old intact male golden retriever dog was presented to the emergency department of a large private-practice specialty hospital. The dog had become cyanotic and collapsed following administration (orogastric tube) of 1.4 mL/kg of hydrogen peroxide 3% to induce emesis for ibuprofen ingestion. The dog had severe methemoglobinemia (33%; reference range: 0.3 to 1.5%) and developed anemia. The methemoglobinemia resolved after 24 h of hospitalization with supportive care. Results from assessment with high-performance liquid chromatography/tandem mass spectrometry were consistent with ibuprofen ingestion, with no acetaminophen detected. Key clinical message: This case demonstrated methemoglobinemia in a dog following both ibuprofen ingestion and hydrogen peroxide 3% administration.
一只8个月大未绝育的雄性金毛猎犬被送到一家大型私人执业专科医院的急诊科。该犬在经口胃管给予1.4 mL/kg的3%过氧化氢以诱导呕吐（因摄入布洛芬）后出现发绀并虚脱。该犬患有严重的高铁血红蛋白血症（33%；参考范围：0.3%至1.5%）并发生贫血。经24小时住院支持治疗后，高铁血红蛋白血症得到缓解。高效液相色谱/串联质谱评估结果与摄入布洛芬一致，未检测到对乙酰氨基酚。关键临床信息：该病例显示犬在摄入布洛芬和给予3%过氧化氢后出现高铁血红蛋白血症。
