智力迟钝者的迟发性运动障碍：与精神分裂症患者群体在患病率、危险因素及分布部位方面的比较。

Tardive dyskinesia in the mentally retarded: comparison of prevalence, risk factors and topography with a schizophrenic population.

作者信息

Cohen S, Khan A, Zheng Y, Chiles J

机构信息

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle.

出版信息

Acta Psychiatr Scand. 1991 Mar;83(3):234-7. doi: 10.1111/j.1600-0447.1991.tb05530.x.

DOI:10.1111/j.1600-0447.1991.tb05530.x

PMID:1674398

Abstract

Thirty mentally retarded patients treated with neuroleptics for aberrant behavior were compared with 30 neuroleptic-treated schizophrenics for the presence, topography and risk factors associated with tardive dyskinesia (TD). In the total sample (n = 60), female sex, schizophrenic diagnosis and increasing age were associated with TD. The length of neuroleptic treatment and current neuroleptic dose were not significantly associated with TD. The only topographical difference in TD presentation was that the mentally retarded group had significantly more tongue involvement.

摘要

将30名因异常行为接受抗精神病药物治疗的智力迟钝患者与30名接受抗精神病药物治疗的精神分裂症患者进行比较，以研究与迟发性运动障碍（TD）相关的存在情况、表现形式和危险因素。在整个样本（n = 60）中，女性、精神分裂症诊断和年龄增长与TD相关。抗精神病药物治疗的时长和当前抗精神病药物剂量与TD无显著关联。TD表现的唯一形态学差异在于，智力迟钝组的舌头受累明显更多。