Farren C K, Dinan T G
Department of Psychiatry, Eastern Health Board, Dublin, Ireland.
Acta Psychiatr Scand. 1994 Sep;90(3):210-3. doi: 10.1111/j.1600-0447.1994.tb01579.x.
The prevalence of dyskinesia in a randomly selected set of 61 mentally handicapped women with a range of diagnoses, levels of IQ and exposure to neuroleptics was assessed using the Abnormal Involuntary Movements Scale (AIMS). Overall, 64% of patients had dyskinesia on the AIMS. There was no correlation with neuroleptic exposure, although 43% of patients had been significantly exposed. There was no correlation between the presence of dyskinesia and the original handicapping diagnosis, and there was no increase in dyskinesia as the patients age increased. There was a significant increase in dyskinesia as IQ fell. This study backs the contention that there is a close association between cognitive impairment and movement disorder.
使用异常不自主运动量表(AIMS)对一组随机选取的61名患有各种诊断、不同智商水平且接触过抗精神病药物的智力障碍女性进行了运动障碍患病率评估。总体而言,64%的患者在AIMS量表上存在运动障碍。虽然43%的患者有显著的抗精神病药物接触史,但运动障碍与抗精神病药物接触无相关性。运动障碍的存在与最初的残疾诊断之间没有相关性,并且随着患者年龄的增加,运动障碍也没有增加。随着智商下降,运动障碍显著增加。这项研究支持了认知障碍与运动障碍之间存在密切关联的观点。