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Multidrug resistance (mdr) genes in human cancer.

作者信息

Nooter K, Herweijer H

机构信息

Department of Pharmacology and Experimental Chemotherapy, Institute of Applied Radiobiology and Immunology TNO, Rijswijk, The Netherlands.

出版信息

Br J Cancer. 1991 May;63(5):663-9. doi: 10.1038/bjc.1991.152.

DOI:10.1038/bjc.1991.152
PMID:1674875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1972385/
Abstract
摘要

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Multidrug resistance (mdr) genes in human cancer.人类癌症中的多药耐药（mdr）基因。
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2
Multidrug resistance and P-glycoprotein expression in human cancer.
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4
Mechanism of multidrug resistance.多药耐药机制。
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P-glycoprotein and multidrug resistance.P-糖蛋白与多药耐药性。
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Genetic basis of multidrug resistance of tumor cells.
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P-glycoproteins in pathology: the multidrug resistance gene family in humans.病理学中的P-糖蛋白：人类多药耐药基因家族
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Multidrug resistance.多重耐药性
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Multidrug resistance: P-glycoprotein and its allies--the elusive foes.
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本文引用的文献

1
Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate.对甲氨蝶呤耐药的中国仓鼠卵巢细胞含有一种对甲氨蝶呤亲和力改变的二氢叶酸还原酶。
Biochemistry. 1980 Sep 2;19(18):4321-7. doi: 10.1021/bi00559a027.
2
CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin.对秋水仙碱、秋水仙酰胺或灰黄霉素具有抗性的CHO突变体具有改变的β-微管蛋白。
Cell. 1980 May;20(1):29-36. doi: 10.1016/0092-8674(80)90231-7.
3
Transport of melphalan by sensitive and resistant L1210 cells.美法仑在敏感和耐药L1210细胞中的转运。
Cancer Res. 1980 Apr;40(4):1144-9.
4
Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.体内衍生的甲氨蝶呤抗性L1210克隆细胞系中转运缺陷表型的相对频率和动力学特性。
Cancer Res. 1981 Nov;41(11 Pt 1):4447-52.
5
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.通过维拉帕米增强长春新碱和长春碱的细胞毒性在体内和体外克服P388白血病对长春新碱的耐药性
Cancer Res. 1981 May;41(5):1967-72.
6
Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.在用钙拮抗剂和钙调蛋白抑制剂孵育后，耐药P388肿瘤细胞中长春新碱和阿霉素的积累增加。
Cancer Res. 1982 Nov;42(11):4730-3.
7
Repair of DNA interstrand crosslinks after busulphan. A possible mode of resistance.
Cancer Chemother Pharmacol. 1982;8(1):3-7. doi: 10.1007/BF00292863.
8
Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues.他莫昔芬及其他三苯乙醇类似物逆转P388小鼠白血病细胞对阿霉素的获得性耐药
Cancer Res. 1984 Oct;44(10):4392-5.
9
Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells.奎尼丁及相关化合物对耐药肿瘤细胞中长春新碱和阿霉素细胞毒性及细胞蓄积的影响。
Cancer Res. 1984 Oct;44(10):4303-7.
10
Potentiation of drug effect by Tween 80 in Chinese hamster cells resistant to actinomycin D and daunomycin.吐温80对耐放线菌素D和柔红霉素的中国仓鼠细胞药物效应的增强作用。
Cancer Res. 1972 Jun;32(6):1195-200.