Drews G N, Bowman J L, Meyerowitz E M
Division of Biology, California Institute of Technology, Pasadena 91125.
Cell. 1991 Jun 14;65(6):991-1002. doi: 10.1016/0092-8674(91)90551-9.
We characterized the distribution of AGAMOUS (AG) RNA during early flower development in Arabidopsis. Mutations in this homeotic gene cause the transformation of stamens to petals in floral whorl 3 and of carpels to another ag flower in floral whorl 4. We found that AG RNA is present in the stamen and carpel primordia but is undetectable in sepal and petal primordia throughout early wild-type flower development, consistent with the mutant phenotype. We also analyzed the distribution of AG RNA in apetela2 (ap2) mutant flowers. AP2 is a floral homeotic gene that is necessary for the normal development of sepals and petals in floral whorls 1 and 2. In ap2 mutant flowers, AG RNA is present in the organ primordia of all floral whorls. These observations show that the expression patterns of the Arabidopsis floral homeotic genes are in part established by regulatory interactions between these genes.
我们对拟南芥早期花发育过程中AGAMOUS（AG）RNA的分布进行了表征。这个同源异型基因的突变会导致花的第三轮中雄蕊转变为花瓣，以及第四轮中雌蕊转变为另一朵ag花。我们发现，在整个野生型花的早期发育过程中，AG RNA存在于雄蕊和雌蕊原基中，但在萼片和花瓣原基中无法检测到，这与突变体表型一致。我们还分析了apetela2（ap2）突变体花中AG RNA的分布。AP2是一个花同源异型基因，对于花的第一轮和第二轮中萼片和花瓣的正常发育是必需的。在ap2突变体花中，AG RNA存在于所有花轮的器官原基中。这些观察结果表明，拟南芥花同源异型基因的表达模式部分是由这些基因之间的调控相互作用建立的。
