Bowman J L, Drews G N, Meyerowitz E M
Division of Biology, California Institute of Technology, Pasadena 91125.
Plant Cell. 1991 Aug;3(8):749-58. doi: 10.1105/tpc.3.8.749.
Mutations in the AGAMOUS (AG) gene cause transformations in two adjacent whorls of the Arabidopsis flower. Petals develop in the third floral whorl rather than the normal stamens, and the cells that would normally develop into the fourth whorl gynoecium behave as if they constituted an ag flower primordium. Early in flower development, AG RNA is evenly distributed throughout third and fourth whorl organ primordia but is not present in the organ primordia of whorls one and two. In contrast to the early expression pattern, later in flower development, AG RNA is restricted to specific cell types within the stamens and carpels as cellular differentiation occurs in those organs. Ectopic AG expression patterns in flowers mutant for the floral homeotic gene APETELA2 (AP2), which regulates early AG expression, suggest that the late AG expression is not directly dependent on AP2 activity.
AGAMOUS（AG）基因的突变会导致拟南芥花的两个相邻轮发生转变。花瓣在第三轮花中发育，而非正常的雄蕊，并且那些通常会发育成第四轮雌蕊的细胞表现得就好像它们构成了一个ag花原基。在花发育早期，AG RNA均匀分布于第三和第四轮器官原基中，但在第一轮和第二轮器官原基中不存在。与早期表达模式不同，在花发育后期，随着雄蕊和心皮中细胞分化的发生，AG RNA局限于这些器官内的特定细胞类型中。对于调控AG早期表达的花同源异型基因APETELA2（AP2）的突变体花中的异位AG表达模式表明，AG的晚期表达并不直接依赖于AP2的活性。
