• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用配备库仑阵列检测器的自动高效液相色谱系统测定生物体液中的神经化学物质。

Determination of neurochemicals in biological fluids by using an automated high-performance liquid chromatographic system with a coulometric array detector.

作者信息

Rizzo V, d'Eril G M, Achilli G, Cellerino G P

机构信息

Servizio Analisi Chimico Cliniche e Neurochimica, IRCCS Istituto Neurologico C. Mondino, Università di Pavia, Italy.

出版信息

J Chromatogr. 1991 Jan 4;536(1-2):229-36. doi: 10.1016/s0021-9673(01)89254-2.

DOI:10.1016/s0021-9673(01)89254-2
PMID:1675641
Abstract

The chromatographic separation of 33 neurochemicals was achieved by using a combined gradient of organic modifier, pH and counter-ion. A secondary separation of unresolved analytes was obtained by using electrochemical detection with a coulometric array of sixteen electrodes. The stability of the analytes was studied and data on analytical performance are reported in addition to a list of neurochemicals detected in a normal plasma sample.

摘要

通过使用有机改性剂、pH值和抗衡离子的组合梯度,实现了33种神经化学物质的色谱分离。通过使用具有16个电极的库仑阵列电化学检测,对未分离的分析物进行了二次分离。研究了分析物的稳定性,并报告了分析性能数据以及在正常血浆样本中检测到的神经化学物质列表。

相似文献

1
Determination of neurochemicals in biological fluids by using an automated high-performance liquid chromatographic system with a coulometric array detector.使用配备库仑阵列检测器的自动高效液相色谱系统测定生物体液中的神经化学物质。
J Chromatogr. 1991 Jan 4;536(1-2):229-36. doi: 10.1016/s0021-9673(01)89254-2.
2
n-Electrode three-dimensional liquid chromatography with electrochemical detection for determination of neurotransmitters.用于测定神经递质的带电化学检测的n电极三维液相色谱法。
Clin Chem. 1984 Sep;30(9):1477-88.
3
Qualitative and quantitative high performance liquid chromatographic analysis of monoamine neurotransmitters and metabolites in cerebrospinal fluid and brain tissue using reductive electrochemical detection.采用还原电化学检测法对脑脊液和脑组织中的单胺类神经递质及其代谢产物进行定性和定量高效液相色谱分析。
Biomed Chromatogr. 1990 Sep;4(5):215-20. doi: 10.1002/bmc.1130040509.
4
Determination of illicit drugs and related substances by high-performance liquid chromatography with an electrochemical coulometric-array detector.
J Chromatogr A. 1996 Apr 5;729(1-2):273-7. doi: 10.1016/0021-9673(95)01095-5.
5
High-performance liquid chromatographic analysis of neurotransmitter amino acids in brain.大脑中神经递质氨基酸的高效液相色谱分析
J Chromatogr. 1988 Jun 24;428(1):9-15. doi: 10.1016/s0378-4347(00)83885-2.
6
Perfluorinated acids as ion-pairing agents in the determination of monoamine transmitters and some prominent metabolites in rat brain by high-performance liquid chromatography with amperometric detection.全氟代酸作为离子对试剂,用于通过高效液相色谱-安培检测法测定大鼠脑中的单胺类神经递质和一些重要代谢物。
J Chromatogr. 1988 Sep 30;449(1):191-205. doi: 10.1016/s0021-9673(00)94379-6.
7
Simultaneous liquid chromatographic determination of seventeen of the major monoamine neurotransmitters, precursors and metabolites. II. Assessment of human brain and cerebrospinal fluid concentrations.
J Chromatogr. 1987 Apr 10;415(2):275-88. doi: 10.1016/s0378-4347(00)83219-3.
8
Determination of neurotransmitter systems in human cerebrospinal fluid and rat nervous tissue by high-performance liquid chromatography with on-line data evaluation.
J Chromatogr. 1984 Jul 13;309(1):53-61. doi: 10.1016/0378-4347(84)80005-5.
9
Determination of clenbuterol and mabuterol in equine plasma by ion-pair liquid chromatography with electrochemical detection. Chromatographic and electrochemical characteristics.
J Chromatogr. 1988 May 27;441(1):197-205. doi: 10.1016/s0021-9673(01)84666-5.
10
[Rapid and sensitive assay of monoamine transmitters and their metabolites in biological samples using high performance liquid chromatography with electrochemical detection].[使用高效液相色谱-电化学检测法对生物样品中单胺类递质及其代谢产物进行快速灵敏的测定]
Sheng Li Xue Bao. 1987 Aug;39(4):412-9.