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日本肉鸡养殖场中耐抗菌药空肠弯曲菌的动态变化

The dynamics of antimicrobial-resistant Campylobacter jejuni on Japanese broiler farms.

作者信息

Ishihara Kanako, Yano Sayoko, Nishimura Maki, Asai Tetsuo, Kojima Akemi, Takahashi Toshio, Tamura Yutaka

机构信息

National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan.

出版信息

J Vet Med Sci. 2006 May;68(5):515-8. doi: 10.1292/jvms.68.515.

Abstract

We investigated for dynamics of Campylobacter clones on 2 different managerial broiler farms. Campylobacter isolates were differentiated by resistance typing and molecular typing methods. On farm I, the same C. jejuni clones resistant to fluoroquinolone and oxytetracycline were isolated after one and half years again and another susceptible clone was invaded. The susceptible clone was isolated again after half year. Broiler flocks on the farm may be repeatedly infected with a few C. jejuni clones. On farm II, new clones including antimicrobial resistant one, were often invaded. The change of predominant C. jejuni clone in each flock on both the farms was observed, in the absence of antimicrobial selective pressure.

摘要

我们调查了两个不同管理方式的肉鸡场弯曲杆菌克隆的动态变化。弯曲杆菌分离株通过耐药分型和分子分型方法进行区分。在农场I,对氟喹诺酮和土霉素耐药的相同空肠弯曲杆菌克隆在一年半后再次被分离出来,并且另一个敏感克隆侵入。敏感克隆在半年后再次被分离出来。该农场的肉鸡群可能会反复感染少数空肠弯曲杆菌克隆。在农场II,包括耐药克隆在内的新克隆经常侵入。在没有抗菌选择压力的情况下,观察到两个农场各鸡群中空肠弯曲杆菌优势克隆的变化。

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