Jarudi N, Golden B, Hoyme J, Tyson M D, Harter J G
Am J Ophthalmol. 1975 May;79(5):790-4. doi: 10.1016/0002-9394(75)90738-2.
One hundred twenty patients who met criteria for presumptive bacterial infections of the conjunctiva were closely recorded for two weeks in a double-blind study that compared the effectiveness of gentamicin with a combination of neomycin and polymyxin B sulfates. The neomycin and polymyxin B combination demonstrated statistical superiority as measured by patient improvement and failure to respond to therapy. However, difficulties including chance distribution of bacteria and variability of organism resistance may have detracted from statistical results.
在一项双盲研究中，对120名符合结膜推定细菌感染标准的患者进行了为期两周的密切记录，该研究比较了庆大霉素与新霉素和硫酸多粘菌素B联合用药的有效性。以患者病情改善情况和对治疗无反应作为衡量标准，新霉素和多粘菌素B联合用药显示出统计学上的优势。然而，包括细菌的随机分布和生物体耐药性的变异性在内的困难可能影响了统计结果。
