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甲氧苄啶-多粘菌素眼药水与新霉素-多粘菌素-短杆菌肽眼药水治疗疑似细菌性结膜炎的双盲研究

Trimethoprim-polymyxin eye drops versus neomycin-polymyxin-gramicidin eye drops in the treatment of presumptive bacterial conjunctivitis - a double-blind study.

作者信息

Genée E, Schlechtweg C, Bauerreiss P, Gibson J R

出版信息

Ophthalmologica. 1982;184(2):92-6. doi: 10.1159/000309190.

Abstract

48 patients witha diagnosis of presumptive bacterial conjunctivitis were assessed. They had been treated with either trimethoprim-polymyxin or neomycin-polymyxin-gramicidin eye drops in a randomised double-blind trial. There were 24 patients in each treatment group. There were no significant differences between the two preparations proved with regard to the eradication of organisms or clinical improvement, and both preparations proved to be very effective. Patient compliance was good and no adverse reactions were encountered with either preparation.

摘要

对48例诊断为疑似细菌性结膜炎的患者进行了评估。在一项随机双盲试验中,他们分别接受了甲氧苄啶-多粘菌素或新霉素-多粘菌素-短杆菌肽眼药水治疗。每个治疗组有24例患者。在根除病原体或临床改善方面,两种制剂之间没有显著差异,且两种制剂都证明非常有效。患者依从性良好,两种制剂均未出现不良反应。

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