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围产期感染与脑瘫

Perinatal infections and cerebral palsy.

作者信息

Hermansen Marcus C, Hermansen Mary Goetz

机构信息

Department of Pediatrics, Dartmouth Medical School, Lebanon, NH 03756-0001, USA.

出版信息

Clin Perinatol. 2006 Jun;33(2):315-33. doi: 10.1016/j.clp.2006.03.002.

DOI:10.1016/j.clp.2006.03.002
PMID:16765727
Abstract

Infections of the mother, the intrauterine environment, the fetus, and the neonate can cause cerebral palsy through a variety of mechanisms. Each of these processes is reviewed. The recently proposed theory of cytokine-induced white matter brain injury and the systemic inflammatory response syndrome with multiple organ dysfunction syndrome is critically evaluated.

摘要

母亲、子宫内环境、胎儿及新生儿的感染可通过多种机制导致脑瘫。本文将对这些过程逐一进行综述。同时,对最近提出的细胞因子诱导的白质脑损伤理论以及伴有多器官功能障碍综合征的全身炎症反应综合征进行批判性评估。

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