Amin Snehal P, Goldberg David J
Skin Laser and Surgery Specialists of NY & NJ, and The Mount Sinai School of Medicine, New York, NY 10022, USA.
J Cosmet Laser Ther. 2006 Jun;8(2):65-8. doi: 10.1080/14764170600717902.
There are few clinical studies directly comparing the efficacy of multiple hair removal systems in the same individual. This study evaluates the efficacy of four highly popular systems for laser hair removal.
In this prospective comparison study, 10 subjects underwent treatment of unwanted hair on the back or thigh. Subjects were skin types I-III, aged 18-55 years. All were treated twice with (1) an intense pulsed light with a red filter; (2) an intense pulsed light with a yellow filter; (3) an 810 nm diode laser; and (4) a 755 nm alexandrite laser. Four treatment areas, using commonly accepted parameters for permanent hair reduction, as well as a control non-treated area were selected. Each treatment area was evaluated with a camera system specifically designed for hair counts at 1, 3, and 6 months after the second treatment by a blinded non-treating physician. Clinical results and adverse events were also noted.
Evaluation of photographs at 1, 3, and 6 months revealed a significant decrease in hair counts (approximately 50%) and hair coverage (approximately 55%). In the hairs that remained after two treatments, no statistical difference was noted in hair length or diameter. There was no statistical difference in efficacy between the four different light devices. Minimal transient adverse effects were noted from all systems. The cryogen spray-based alexandrite laser showed the highest pain scores.
Although hair removal with commonly used systems is, as expected, highly effective, treatment with light-based devices can cause less pain, yet show efficacy similar to laser systems.
直接比较多种脱毛系统在同一个体中的疗效的临床研究较少。本研究评估了四种广受欢迎的激光脱毛系统的疗效。
在这项前瞻性比较研究中，10名受试者接受了背部或大腿多余毛发的治疗。受试者为I-III型皮肤，年龄在18至55岁之间。所有受试者均接受了两次治疗，分别使用（1）带红色滤光片的强脉冲光；（2）带黄色滤光片的强脉冲光；（3）810nm二极管激光；以及（4）755nm翠绿宝石激光。选择了四个治疗区域，采用公认的永久性脱毛参数进行治疗，并设置了一个未治疗的对照区域。在第二次治疗后的1、3和6个月，由一位不知情的非治疗医生使用专门设计用于毛发计数的摄像系统对每个治疗区域进行评估。同时记录临床结果和不良事件。
对1、3和6个月时的照片评估显示，毛发数量（约50%）和毛发覆盖面积（约55%）显著减少。在两次治疗后仍留存的毛发中，毛发长度或直径未发现统计学差异。四种不同的光设备在疗效上没有统计学差异。所有系统均记录到最小程度的短暂不良反应。基于冷冻剂喷雾的翠绿宝石激光疼痛评分最高。
尽管如预期的那样，使用常用系统进行脱毛非常有效，但使用光设备治疗引起的疼痛较小，且疗效与激光系统相似。
