Tan Jeremy T H, Suyapto Dion R, Neo Eu L, Leong Paul S K
Department of General Surgery, Lyell McEwin Hospital, Adelaide, South Australia, Australia.
ANZ J Surg. 2006 May;76(5):335-8. doi: 10.1111/j.1445-2197.2006.03721.x.
Laparoscopic cholecystectomy is now the gold standard procedure for symptomatic gallstone disease. Nevertheless, there are still several controversies such as the need for routine intraoperative cholangiogram (IOC), the indications for and results of early laparoscopic cholecystectomy in the setting of acute cholecystitis and the use of endoscopic retrograde cholangiopancreatography versus laparoscopic common bile duct (CBD) exploration for intraoperatively detected choledocholithiasis. The aim of this study was to investigate some of these controversies.
All laparoscopic cholecystectomies carried out at our institution, a secondary referral centre in Adelaide, South Australia, over a 9-month period were prospectively audited. Data were collected regarding indications for surgery, rate of conversion to open operation, use of IOC, rate of choledocholithiasis and complication rate.
There were 202 patients, of whom 152 were women and 50 men. Age range was 15-83 years. Sixty-one per cent of emergency operations were for acute cholecystitis. The conversion rate for emergency operations was 20.6% and for elective procedures was 4.2% (P = 0.003). One hundred and eighty-four patients had an IOC performed. Twelve of these patients had choledocholithiasis. Six of these 12 patients had both normal preoperative ultrasound and liver function tests. Four of the patients went on to postoperative endoscopic retrograde cholangiopancreatography, four had successful laparoscopic CBD exploration, two had open CBD exploration and two had their distal CBD filling defects flushed away with normal saline. There was no morbidity associated with performance of the IOC. There were three patients with postoperative bile leak and one with a bile duct injury.
Selective IOC would miss a proportion of patients with choledocholithiasis. Early laparoscopic cholecystectomy for acute cholecystitis is associated with a higher conversion rate than elective laparoscopic cholecystectomy. Overall complication rate is low, with 95% of patients having no complications. Laparoscopic CBD exploration is feasible with a reasonable success rate. This can all be achieved at a secondary referral centre staffed by general surgeons.
腹腔镜胆囊切除术目前是有症状胆结石疾病的金标准术式。然而,仍存在一些争议,如是否需要常规术中胆管造影(IOC)、急性胆囊炎情况下早期腹腔镜胆囊切除术的适应证及结果,以及术中发现胆总管结石时内镜逆行胰胆管造影术与腹腔镜胆总管(CBD)探查术的应用。本研究旨在探讨其中一些争议。
对在我们机构(位于南澳大利亚阿德莱德的二级转诊中心)9个月期间进行的所有腹腔镜胆囊切除术进行前瞻性审核。收集了有关手术适应证、转为开放手术的比率、IOC的使用、胆总管结石发生率及并发症发生率的数据。
共有202例患者,其中女性152例,男性50例。年龄范围为15 - 83岁。61%的急诊手术是针对急性胆囊炎。急诊手术的转换率为20.6%,择期手术的转换率为4.2%(P = 0.003)。184例患者进行了IOC。其中12例患者有胆总管结石。这12例患者中有6例术前超声和肝功能检查均正常。4例患者术后接受了内镜逆行胰胆管造影术,4例成功进行了腹腔镜CBD探查,2例进行了开放CBD探查,2例通过生理盐水冲洗清除了胆总管远端充盈缺损。IOC的实施未导致任何发病率增加。有3例患者术后发生胆漏,1例发生胆管损伤。
选择性IOC会遗漏一部分胆总管结石患者。急性胆囊炎的早期腹腔镜胆囊切除术比择期腹腔镜胆囊切除术的转换率更高。总体并发症发生率较低,95%的患者无并发症。腹腔镜CBD探查是可行的,成功率合理。这一切都可以在由普通外科医生组成的二级转诊中心实现。