Voyles C R, Sanders D L, Hogan R
Surgical Clinic Associates, Unviersity of Mississippi, Jackson.
Ann Surg. 1994 Jun;219(6):744-50; discussion 750-2.
The authors documented the evolution of common bile duct (CBD) evaluation after the development of laparoscopic cholecystectomy (LC) and CBD exploration. Emphasis was placed on stratification of CBD stone risk so that subgroups could be selected appropriately for no further studies, preoperative endoscopic retrograde cholangiogram (ERC), or intraoperative intervention.
Data were accumulated by the authors on presentation, findings, and outcomes of 1050 patients who underwent cholecystectomies. Risk stratification was based on the history, ultrasound findings, biochemical derangements, and operative findings.
Fifty-seven per cent of patients met criteria to be "no/low" risk for CBD stones (CBD diameter < 5 mm, normal liver enzymes, and no history of acute cholecystitis, jaundice, or pancreatitis); in these patients, cholangiograms were not obtained, and there was no clinical evidence of CBD stones observed in follow-up at 45 months (sensitivity = 100%). As techniques developed for laparoscopic CBD exploration, there was a decreased incidence of open cholecystectomy (p < 0.05) and preoperative ERC (p < 0.05). The rate of operative cholangiogram increased from 13% to 23% during the series (p < 0.01). There were no CBD injuries or late strictures. The only bile leak occurred from a peripheral segmental duct in the gallbladder bed and was resolved with a laparotomy and suture. There were no transfusions. Three retained stones were documented in patients who had false-normal operative cholangiograms.
Criteria were defined that delineate a "no/low" risk group of LC patients for whom operative cholangiograms were not indicated for excluding CBD stones. The routine use of operative cholangiography as a means of preventing CBD injury was not substantiated by this study. The indications for preoperative ERC should continue to decrease as laparoscopic techniques evolve.
作者记录了腹腔镜胆囊切除术(LC)和胆总管探查术发展后胆总管(CBD)评估方法的演变。重点是对CBD结石风险进行分层,以便为无需进一步检查、术前内镜逆行胆管造影(ERC)或术中干预的患者进行适当分组。
作者收集了1050例行胆囊切除术患者的临床表现、检查结果及预后数据。风险分层基于病史、超声检查结果、生化指标异常及手术所见。
57%的患者符合CBD结石“无/低”风险标准(CBD直径<5mm、肝酶正常、无急性胆囊炎、黄疸或胰腺炎病史);这些患者未进行胆管造影,在45个月的随访中未观察到CBD结石的临床证据(敏感性=100%)。随着腹腔镜CBD探查技术的发展,开腹胆囊切除术(p<0.05)和术前ERC(p<0.05)的发生率降低。术中胆管造影率在该系列研究期间从13%升至23%(p<0.01)。未发生CBD损伤或晚期狭窄。唯一的胆漏发生在胆囊床的外周段胆管,经开腹手术和缝合后治愈。未进行输血。在手术胆管造影结果假阴性的患者中发现3例残留结石。
确定了界定LC患者“无/低”风险组的标准,对于该组患者无需进行手术胆管造影以排除CBD结石。本研究未证实将手术胆管造影作为预防CBD损伤的常规手段的合理性。随着腹腔镜技术的发展,术前ERC的指征应继续减少。