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水痘疫苗病毒在一家儿童慢性病护理机构中的二次传播。

Secondary transmission of varicella vaccine virus in a chronic care facility for children.

作者信息

Grossberg Richard, Harpaz Rafael, Rubtcova Elena, Loparev Vladimir, Seward Jane F, Schmid D Scott

机构信息

Hattie Larlham Center for Children With Disabilities, Mantua, Ohio, USA.

出版信息

J Pediatr. 2006 Jun;148(6):842-4. doi: 10.1016/j.jpeds.2006.01.038.

Abstract

A 16-year-old varicella-seronegative resident at a chronic care facility received varicella vaccine; 15 days later he developed severe varicella. Subsequently, a 13-year-old resident and a 39-year-old health care worker developed mild varicella. We demonstrate that vaccine-strain virus was transmitted to both persons, and that transmission included at least 2 variant vaccine strains.

摘要

一名长期护理机构的16岁水痘血清学阴性居民接种了水痘疫苗;15天后,他患上了重症水痘。随后,一名13岁居民和一名39岁医护人员患上了轻度水痘。我们证明疫苗株病毒传播给了这两人,且传播至少包括2种变异疫苗株。

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