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优化脑转移瘤患者的治疗方案。

Optimizing therapy for patients with brain metastases.

作者信息

Kuo Timothy, Recht Lawrence

机构信息

Department of Medical Oncology, Stanford University Medical School, Palo Alto, CA 94305, USA.

出版信息

Semin Oncol. 2006 Jun;33(3):299-306. doi: 10.1053/j.seminoncol.2006.03.005.

DOI:10.1053/j.seminoncol.2006.03.005
PMID:16769418
Abstract

Brain metastases from systemic cancers are the most common malignant brain tumors encountered. Although prognosis remains poor, it is possible to stratify patients according to risk. Furthermore, an aggressive therapeutic approach for good-risk patients that includes a combination of either surgery or stereotactic radiosurgery (SRS) and whole brain radiation therapy (WBRT) can improve survival and decrease the risk of central nervous system progression.

摘要

系统性癌症的脑转移是最常见的恶性脑肿瘤。尽管预后仍然很差,但根据风险对患者进行分层是可能的。此外,对于低风险患者采用积极的治疗方法,包括手术或立体定向放射外科(SRS)与全脑放射治疗(WBRT)联合使用,可以提高生存率并降低中枢神经系统进展的风险。

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引用本文的文献

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Intracranial Metastatic Disease: Present Challenges, Future Opportunities.颅内转移性疾病:当前挑战与未来机遇
Front Oncol. 2022 Mar 7;12:855182. doi: 10.3389/fonc.2022.855182. eCollection 2022.
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Management evaluation of metastasis in the brain (MEMBRAIN)-a United Kingdom and Ireland prospective, multicenter observational study.脑转移管理评估(MEMBRAIN)——一项英国和爱尔兰的前瞻性多中心观察性研究。
Neurooncol Pract. 2020 Jun;7(3):344-355. doi: 10.1093/nop/npz063. Epub 2019 Dec 6.
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Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases.
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Anticancer Agents Med Chem. 2016;16(7):810-5. doi: 10.2174/1871520616666151120121928.
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