一种来自梅花鹿的新型多肽，可促进表皮细胞和NIH3T3细胞系的增殖。
A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line.
作者信息
Guan Shu-Wen, Duan Leng-Xin, Li Yuan-Yuan, Wang Ben-Xiang, Zhou Qiu-Li
机构信息
Laboratory of Biological Macromolecule, College of Life Science, Changchun, China.
出版信息
Acta Biochim Pol. 2006;53(2):395-7. Epub 2006 Jun 12.
A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg x L(-1) and 5-80 mg x L(-1), respectively).
从梅花鹿（Cervus nippon Temminck）的鹿茸中分离出一种对某些细胞增殖有刺激作用的新型多肽——鹿茸多肽（VAPPs）。该多肽由一条含32个氨基酸残基的单链组成：VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM。VAPPs对大鼠表皮细胞和NIH3T3细胞系显示出显著的刺激作用（剂量范围分别为10 - 40 mg·L⁻¹和5 - 80 mg·L⁻¹）。
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