Hodgkinson D W, Jellett L B, Ashby R H
Accident and Emergency Department, Royal Brisbane Hospital, Australia.
Arch Emerg Med. 1991 Mar;8(1):8-16. doi: 10.1136/emj.8.1.8.
Two-hundred and eighty-nine patients who made a total of 323 presentations to the Royal Brisbane Hospital Accident and Emergency Department with a known or suspected oral drug overdose were reviewed. The majority of patients (76%) could be managed in a 24 h Accident and Emergency observation unit. Activated charcoal given orally or via a nasogastric tube was the recommended method of preventing further absorption of an ingested drug. The use of syrup of ipecac was not encouraged and orogastric lavage was used in only specific situations. The morbidity and mortality of these patients when compared with other studies, was not adversely affected by this protocol which dramatically reduced the indications for the use of orogastric lavage and syrup of ipecac.
对289名患者进行了回顾，这些患者共323次前往皇家布里斯班医院急诊科，已知或疑似口服药物过量。大多数患者（76%）可在24小时急诊科观察单元进行处理。口服或通过鼻胃管给予活性炭是推荐的预防摄入药物进一步吸收的方法。不鼓励使用吐根糖浆，仅在特定情况下使用胃灌洗。与其他研究相比，这些患者的发病率和死亡率并未因该方案而受到不利影响，该方案显著减少了胃灌洗和吐根糖浆的使用指征。
