Thompson A M, Robins J B, Prescott L F
Hum Toxicol. 1987 May;6(3):215-8. doi: 10.1177/096032718700600307.
Cardiorespiratory function in 42 patients admitted to the Regional Poisoning Treatment Centre, Edinburgh who underwent gastric lavage for self poisoning, was studied using an electrocardiograph and an ear oximeter. Mean pulse rate rose from 92 to 121 beats per min and the mean partial pressure of oxygen fell from 95 to 80 mmHg during lavage (P less than 0.001). These changes were significantly greater in conscious than unconscious patients, in smokers than in non-smokers and most marked in male smokers aged 45 or older. No sex or age differences were noted. Electrocardiograph changes were noted in 41% of patients, including potentially serious changes in 2 patients. The indications for gastric lavage should probably be reviewed particularly in conscious older patients who smoke and due consideration given to induced emesis and ingestion of activated charcoal as alternatives.
对爱丁堡地区中毒治疗中心收治的42例因自我中毒接受洗胃的患者，使用心电图仪和耳部血氧仪对其心肺功能进行了研究。洗胃期间，平均脉搏率从每分钟92次升至121次，平均氧分压从95 mmHg降至80 mmHg（P<0.001）。这些变化在清醒患者中比昏迷患者更显著，在吸烟者中比不吸烟者更显著，在45岁及以上的男性吸烟者中最为明显。未发现性别和年龄差异。41%的患者出现心电图变化，其中2例有潜在的严重变化。洗胃的指征可能需要重新评估，尤其是对清醒的老年吸烟者，应适当考虑采用催吐和服用活性炭作为替代方法。
