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通过免疫层析法检测胸腔积液样本中肺炎球菌抗原对肺炎球菌肺炎诊断的实用性。

Usefulness of pneumococcal antigen detection in pleural fluid samples by immunochromatographic assay for diagnosis of pneumococcal pneumonia.

作者信息

Andreo F, Domínguez J, Ruiz-Manzano J, Prat C, Blanco S, Lores L, Sánchez M D, Latorre I, Giménez M, Ausina V

机构信息

Servei de Pneumologia, Hospital de Sant Boi, Barcelona, Spain.

出版信息

Clin Microbiol Infect. 2006 Jul;12(7):682-4. doi: 10.1111/j.1469-0691.2006.01484.x.

DOI:10.1111/j.1469-0691.2006.01484.x
PMID:16774569
Abstract

This study investigated the utility of an immunochromatographic test (ICT) for the detection of Streptococcus pneumoniae antigens in pleural fluid. Antigen was detected in 15 of 19 (79%) patients with pneumococcal pneumonia. The ICT was always negative in patients with non-pneumococcal pneumonia, but was positive in three cases with a non-infectious aetiology. In patients with pneumonia for which no pathogen was identified, antigen was detected in one of 24 pleural fluids tested. The ICT can be a valuable tool for the management of pneumonia because it can detect pneumococcal antigen in pleural effusion samples.

摘要

本研究调查了免疫层析试验(ICT)在检测胸腔积液中肺炎链球菌抗原方面的效用。19例肺炎球菌肺炎患者中有15例(79%)检测到抗原。ICT在非肺炎球菌肺炎患者中始终为阴性,但在3例非感染性病因患者中呈阳性。在未鉴定出病原体的肺炎患者中,24份检测的胸腔积液中有1份检测到抗原。ICT可为肺炎的管理提供有价值的工具,因为它可在胸腔积液样本中检测到肺炎球菌抗原。

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