Pinta P, Offenstadt G, Lesage D, Coutant P, Bencharif G, Amstutz P
Rev Fr Mal Respir. 1983;11(1):39-45.
We studied the diagnostic value of the detection of soluble pneumococcal antigens by counter-immunoelectrophoresis (ES) in patients with pneumonia. Pneumococcal antigens were detected in blood, urine and pleural fluid. 59 patients were distributed into 3 groups: (Group 1) - 19 patients with a non-pneumococcal, but bacteriologically-proven pneumonia, (Group 2)-32 patients with a bacteriologically confirmed pneumococcal pneumonia, (Group 3)-8 patients with a non-bacteriologically proven pneumonia, but with pneumococcal antigens. No Group 1 patients had pneumococcal antigens. In Group 2 pneumococcal antigens were present in 15 cases. The sensitivity of ES in the detection of soluble pneumococcal antigens (APS) in the blood, urine and pleural fluid during pneumococcal pneumonias was 57.5%. There was a diagnostic benefit when compared to bacteriological analysis alone of 20%. We believe that ES is a useful complementary examination to classical bacteriology.
我们研究了对流免疫电泳（ES）检测可溶性肺炎球菌抗原在肺炎患者中的诊断价值。在血液、尿液和胸液中检测到了肺炎球菌抗原。59例患者被分为3组：（第1组）-19例非肺炎球菌性但经细菌学证实的肺炎患者，（第2组）-32例经细菌学证实的肺炎球菌肺炎患者，（第3组）-8例未经细菌学证实但有肺炎球菌抗原的肺炎患者。第1组患者均无肺炎球菌抗原。第2组中有15例存在肺炎球菌抗原。肺炎球菌肺炎期间，ES检测血液、尿液和胸液中可溶性肺炎球菌抗原（APS）的敏感性为57.5%。与单独的细菌学分析相比，有20%的诊断益处。我们认为ES是对经典细菌学有用的补充检查。
