Kreutzer R D, Corredor A, Grimaldi G, Grogl M, Rowton E D, Young D G, Morales A, McMahon-Pratt D, Guzman H, Tesh R B
Department of Biology, Youngstown State University, Ohio.
Am J Trop Med Hyg. 1991 Jun;44(6):662-75. doi: 10.4269/ajtmh.1991.44.662.
Characterization of Leishmania colombiensis sp.n. is presented, which on the basis of biological and molecular criteria, appears to be a new member of the L. braziliensis complex. A total of nine isolates of the new parasite were made in Colombia and Panama between 1980 and 1986: two from human cases of cutaneous leishmaniasis, six from phlebotomine sand flies, and one from a sloth. Although most closely related to L. lainsoni, L. colombiensis sp.n. is clearly distinguishable from other members of the genus by its reactivity with monoclonal antibodies, isoenzyme electrophoresis, and restriction endonuclease fragment patterns of kinetoplast DNA (k-DNA).
本文介绍了新种哥伦比亚利什曼原虫的特征，根据生物学和分子标准，它似乎是巴西利什曼原虫复合体的一个新成员。1980年至1986年间，在哥伦比亚和巴拿马共分离出9株这种新寄生虫：2株来自皮肤利什曼病患者，6株来自白蛉，1株来自树懒。尽管哥伦比亚利什曼原虫与赖氏利什曼原虫关系最为密切，但通过其与单克隆抗体的反应性、同工酶电泳以及动质体DNA（k-DNA）的限制性内切酶片段模式，它与该属的其他成员明显不同。
