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采用 Cotrel-Dubousset 器械进行脊柱融合术治疗脑瘫患者的神经性脊柱侧弯。

Spinal fusion with Cotrel-Dubousset instrumentation for neuropathic scoliosis in patients with cerebral palsy.

作者信息

Teli Marco G A, Cinnella Pasquale, Vincitorio Fiammetta, Lovi Alessio, Grava Giuseppe, Brayda-Bruno Marco

机构信息

Galeazzi Orthopaedic Institute, Milan, Italy.

出版信息

Spine (Phila Pa 1976). 2006 Jun 15;31(14):E441-7. doi: 10.1097/01.brs.0000221986.07992.fb.

Abstract

STUDY DESIGN

Retrospective.

OBJECTIVE

To report on the treatment of patients with cerebral palsy and neuropathic scoliosis with third-generation instrumented spinal fusion by Cotrel-Dubousset instrumentation.

SUMMARY OF BACKGROUND DATA

Second-generation instrumented spinal fusion is considered the standard for progressive neuropathic scoliosis in cerebral palsy, despite high complication rates. Evidence is needed to evaluate the increasing use of third-generation instrumented spinal fusion in similar patients.

METHODS

Patients with cerebral palsy and spinal deformity treated consecutively by 1 surgeon with Cotrel-Dubousset instrumentation and minimum 2-year follow-up were reviewed. An outcome questionnaire was administered at final follow-up.

RESULTS

A total of 60 patients were included. Mean age was 15 years at surgery. Mean follow-up was 79 months. There were 26 anteroposterior and 34 posterior-only procedures. Correction of coronal deformity and pelvic obliquity averaged 60% and 40%, respectively. Major complications affected 13.5% of patients, and included implant loosening, deep infection, and pseudarthrosis. Minor complications affected 10% of patients. Outcome questionnaires showed marked improvements in the areas of satisfaction, function, and quality of life after surgery.

CONCLUSIONS

Segmental, third-generation instrumented spinal fusion provides lasting correction of spinal deformity and improved quality of life in patients with cerebral palsy and neuropathic scoliosis, with a lower pseudarthrosis rate compared to reports on second-generation instrumented spinal fusion.

摘要

研究设计

回顾性研究。

目的

报告采用 Cotrel-Dubousset 器械进行第三代器械辅助脊柱融合术治疗脑瘫合并神经病理性脊柱侧弯患者的情况。

背景资料总结

尽管并发症发生率较高,但第二代器械辅助脊柱融合术仍被认为是脑瘫患者进行性神经病理性脊柱侧弯的治疗标准。需要证据来评估在类似患者中越来越多地使用第三代器械辅助脊柱融合术的情况。

方法

回顾了由 1 名外科医生连续采用 Cotrel-Dubousset 器械治疗且随访至少 2 年的脑瘫合并脊柱畸形患者。在末次随访时进行了结果问卷调查。

结果

共纳入 60 例患者。手术时的平均年龄为 15 岁。平均随访时间为 79 个月。有 26 例前后路联合手术和 34 例单纯后路手术。冠状面畸形和骨盆倾斜的矫正率平均分别为 60%和 40%。主要并发症发生率为 13.5%,包括内固定松动、深部感染和假关节形成。次要并发症发生率为 10%。结果问卷调查显示,术后患者在满意度、功能和生活质量方面有显著改善。

结论

节段性第三代器械辅助脊柱融合术能持久矫正脑瘫合并神经病理性脊柱侧弯患者的脊柱畸形并改善生活质量,与第二代器械辅助脊柱融合术的报告相比,假关节形成率更低。

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