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2
Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments.
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Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics.
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Rad54 protein exerts diverse modes of ATPase activity on duplex DNA partially and fully covered with Rad51 protein.
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Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament.
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In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation.
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Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament.
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A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament.
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9
Functions of the Snf2/Swi2 family Rad54 motor protein in homologous recombination.
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RAD54 controls access to the invading 3'-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae.
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The Eukaryotic homology search complex distorts donor DNA structure to probe for homology.
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Local structural dynamics of Rad51 protomers revealed by cryo-electron microscopy of Rad51-ssDNA filaments.
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Concurrent D-loop cleavage by Mus81 and Yen1 yields half-crossover precursors.
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Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair.
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E2F1 Promotes Progression of Bladder Cancer by Modulating RAD54L Involved in Homologous Recombination Repair.
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Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length.
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The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair.
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DNA damage response and repair in perspective: Aedes aegypti, Drosophila melanogaster and Homo sapiens.
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本文引用的文献
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Rad54: the Swiss Army knife of homologous recombination?
Nucleic Acids Res. 2006;34(15):4115-25. doi: 10.1093/nar/gkl481. Epub 2006 Aug 25.
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Visualization of Rad54, a chromatin remodeling protein, translocating on single DNA molecules.
Mol Cell. 2006 Jul 7;23(1):143-8. doi: 10.1016/j.molcel.2006.05.009.
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X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA.
Cell. 2005 May 6;121(3):363-73. doi: 10.1016/j.cell.2005.03.026.
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Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54.
Nat Struct Mol Biol. 2005 Apr;12(4):350-6. doi: 10.1038/nsmb919. Epub 2005 Apr 3.
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Organized unidirectional waves of ATP hydrolysis within a RecA filament.
PLoS Biol. 2005 Feb;3(2):e52. doi: 10.1371/journal.pbio.0030052. Epub 2005 Feb 8.
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Sequence-directed DNA translocation by purified FtsK.
Science. 2005 Jan 28;307(5709):586-90. doi: 10.1126/science.1104885.
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Multiple pathways process stalled replication forks.
Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12783-8. doi: 10.1073/pnas.0401586101. Epub 2004 Aug 24.
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Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer?
Curr Opin Genet Dev. 2004 Apr;14(2):165-73. doi: 10.1016/j.gde.2004.01.007.
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NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities.
Anal Biochem. 2003 Oct 15;321(2):266-71. doi: 10.1016/s0003-2697(03)00461-5.
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Rad54, a Jack of all trades in homologous recombination.
DNA Repair (Amst). 2003 Jul 16;2(7):787-94. doi: 10.1016/s1568-7864(03)00070-3.
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