Bozkurt Nuray, Yilmaz Ercan, Biri Aydan, Taner Zeki, Himmetoğlu Ozdemir
Department of Gynecology and Obstetrics, Faculty of Medicine, Gazi University, Turkey.
J Thromb Thrombolysis. 2006 Aug;22(1):51-4. doi: 10.1007/s11239-006-8322-2.
To compare the platelet count and mean platelet volume (MPV) values of pregnancies diagnosed with gestational diabetes with those of healthy pregnancies.
MATERIAL-METHOD: Between June 2003 and September 2004, 100 healthy pregnancies and 100 pregnancies with gestational diabetes were studied at Gazi University, Department of Obstetrics and Gynecology.
While no statistically significant difference was observed in the platelet count between the two groups, the MPV of the gestational diabetes group (9.4 +/- 1.6 fl) was evaluated to be significantly higher than the MPV of the healthy pregnancy group (8.3 +/- 1.1 fl). Additionally, when linear regression analysis was performed an inverse relationship was observed between platelet number and MPV.
There is a need for further research focusing on the platelet function in the observation and treatment of gestational diabetes, which can pose the risk of developing Type 2 diabetes for the mother and has negative consequences for the fetus.
比较诊断为妊娠期糖尿病的孕妇与健康孕妇的血小板计数及平均血小板体积（MPV）值。
2003年6月至2004年9月期间，在加齐大学妇产科对100例健康孕妇和100例妊娠期糖尿病孕妇进行了研究。
两组之间血小板计数未观察到统计学显著差异，但妊娠期糖尿病组的MPV（9.4±1.6fl）显著高于健康妊娠组的MPV（8.3±1.1fl）。此外，进行线性回归分析时，观察到血小板数量与MPV之间呈负相关。
妊娠期糖尿病可能会使母亲患2型糖尿病的风险增加，并对胎儿产生负面影响，因此需要进一步研究聚焦于妊娠期糖尿病观察和治疗中的血小板功能。
