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用奥曲肽治疗胰腺假性囊肿。

Treatment of pancreatic pseudocysts with octreotide.

作者信息

Gullo L, Barbara L

出版信息

Lancet. 1991 Aug 31;338(8766):540-1. doi: 10.1016/0140-6736(91)91102-z.

DOI:10.1016/0140-6736(91)91102-z
PMID:1678802
Abstract

Pancreatic pseudocysts are a common and painful complication of chronic pancreatitis. Seven patients (six male, one female; mean age 49.9 years) with chronic pancreatitis complicated by pseudocysts and persistent pain were treated with the pancreatic anti-secretory drug octreotide for 2 weeks. Octreotide caused no notable changes in the size of the pseudocysts of three patients. In the remaining four patients, the pseudocysts decreased in size by a mean of 42% (range 29-52%), and pain disappeared completely. These findings suggest a role for octreotide in the treatment of pancreatic pseudocysts.

摘要

胰腺假性囊肿是慢性胰腺炎常见且疼痛的并发症。7例(6例男性,1例女性;平均年龄49.9岁)慢性胰腺炎合并假性囊肿且持续疼痛的患者接受了胰腺分泌抑制剂奥曲肽治疗2周。奥曲肽对3例患者的假性囊肿大小未产生显著变化。在其余4例患者中,假性囊肿大小平均减小42%(范围29%-52%),且疼痛完全消失。这些发现提示奥曲肽在胰腺假性囊肿治疗中具有一定作用。

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