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生长抑素类似物(善宁)在经皮穿刺引流胰腺假性囊肿中的应用

[The use of a somatostatin analog (Sandostatin) in percutaneous drainage of pancreatic pseudocysts].

作者信息

Mádi Szabó L, Pásztor J

机构信息

Gasztroenterológiai Ultraszonográfiás Részleg, Pest megyei Budagyöngye Kórház, Budapest.

出版信息

Orv Hetil. 1993 Sep 5;134(36):1977-84.

PMID:8367149
Abstract

The inflammatory pancreatic diseases are usually hardly governable; special problems are arosen with the treatment of pancreatic fluid collections. The focal pericystic pancreatitis, the reactive inflammation developing in the course of the injury of the gland as well as draining pancreatic duct filling the cyst up may result in pitfalls. Thus subcutaneous administration of Sandostatin was added to the usual therapeutic regimen in 12 patients. It was applied with external and internal drainage of pseudocysts in 10 patients and in one of them the complication was reduced in an unsuccessful attempt, respectively. The pseudocyst of one patient disappeared by sole somatostatin administration. One cystic formation did not respond to this kind of treatment thus a drainage procedure had to be performed. Based on our initial experiences we seem to find a rather promising tool that may influence the basic process beneficially and makes our instrumental interventions safer and more successful.

摘要

炎症性胰腺疾病通常很难控制;胰腺液体积聚的治疗出现了一些特殊问题。局灶性囊肿周围胰腺炎、腺体损伤过程中发生的反应性炎症以及引流胰管使囊肿充盈,都可能导致问题。因此,在12例患者的常规治疗方案中加入了善宁皮下注射。10例患者在进行假性囊肿内、外引流时使用了善宁,其中1例患者在一次未成功的尝试中并发症有所减少。1例患者的假性囊肿仅通过使用生长抑素就消失了。1个囊性结构对此种治疗无反应,因此不得不进行引流手术。基于我们最初的经验,我们似乎找到了一种很有前景的工具,它可能对基本过程产生有益影响,并使我们的器械干预更安全、更成功。

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