Wiebels D, Turnbull K, Steinkraus V, Böer A
Dermatologikum Hamburg, Stephansplatz 5, 20354 Hamburg.
Hautarzt. 2007 Mar;58(3):237-40. doi: 10.1007/s00105-006-1130-y.
A 66-year-old woman presented with erythematous nodules on both legs and told of a history of lymph node tuberculosis that had been treated with surgery and tuberculostatic therapy years before. A biopsy taken from a nodule showed nodular vasculitis. PCR for Mycobacterium tuberculosis-specific DNA on the paraffin-embedded tissue was positive. Based on the experience with our patient, positive PCR results for Mycobacterium tuberculosis-specific DNA in lesions of nodular vasculitis are discussed critically. The historical background of "tuberculids", such as erythema induratum Bazin, is elucidated.
一名66岁女性双下肢出现红斑结节,自述多年前有淋巴结结核病史,曾接受手术及抗结核治疗。取自一个结节的活检显示为结节性血管炎。石蜡包埋组织的结核分枝杆菌特异性DNA聚合酶链反应(PCR)结果呈阳性。基于我们对该患者的经验,对结节性血管炎病变中结核分枝杆菌特异性DNA的PCR阳性结果进行了批判性讨论。阐述了诸如硬结性红斑(巴赞红斑)等“结核疹”的历史背景。