Mascaró José M, Baselga Eulalia
Department of Dermatology, Hospital Clínico and Barcelona University School of Medicine, Calle Villarroel 170, 08036 Barcelona, Spain.
Dermatol Clin. 2008 Oct;26(4):439-45, v. doi: 10.1016/j.det.2008.05.007.
Erythema induratum of Bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of tuberculid occurring on the legs, whereas nodular vasculitis represents the nontuberculous counterpart. The number of reports of erythema induratum of Bazin is decreasing in most developed countries in accordance with the decreased incidence of tuberculosis. The etiopathogenesis of erythema induratum of Bazin and its relation to tuberculosis are still controversial, because mycobacteria cannot be cultured from the skin lesions. Most authors currently consider erythema induratum of Bazin (nodular vasculitis) a multifactorial disorder with many different causes, tuberculosis being one of them.
巴津硬红斑是一种慢性结节性皮疹,通常发生在年轻女性的小腿上。它被认为是结核菌素超敏反应的一种表现,是发生在腿部的一种结核疹,而结节性血管炎则是其非结核性对应物。在大多数发达国家,随着结核病发病率的下降,巴津硬红斑的报告数量也在减少。巴津硬红斑的发病机制及其与结核病的关系仍存在争议,因为在皮肤病变中无法培养出分枝杆菌。目前大多数作者认为巴津硬红斑(结节性血管炎)是一种多因素疾病,有许多不同的病因,结核病是其中之一。