Friesen P, Scotti P, Longworth J, Rueckert R
Biophysics Laboratory of the Graduate School and Biochemistry Department of the College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706.
J Virol. 1980 Sep;35(3):741-7. doi: 10.1128/JVI.35.3.741-747.1980.
Black beetle virus (BBV), one of a recently discovered class of viruses with a bipartite genome, multiplied readily in Schneider's line 1 of Drosophila cells. Virus yields, on the order of 100 mg per liter of culture, were unusually high and represented some 20% of the total cell protein within 3 days after infection. A derivative subline of these Drosophila cells was found to be resistant to infection by BBV. These resistant cells were also found to carry small amounts of BBV-related particles, possibly a maturation-defective form of BBV.
黑甲虫病毒（BBV）是最近发现的一类具有双分体基因组的病毒之一，能在果蝇细胞的施耐德1号线中轻易繁殖。病毒产量约为每升培养物100毫克，异常之高，在感染后3天内约占细胞总蛋白的20%。人们发现这些果蝇细胞的一个衍生亚系对BBV感染具有抗性。还发现这些抗性细胞携带少量与BBV相关的颗粒，可能是一种成熟缺陷型的BBV。
