Henry Charles S
Department of Chemistry, Colorado State University, Fort Collins, CO, USA.
Methods Mol Biol. 2006;339:1-10. doi: 10.1385/1-59745-076-6:1.
Microchip capillary electrophoresis emerged in the early 1990s as an interesting and novel approach to the high-speed separation of biological compounds, including DNA and proteins. Since the early development in this area, growth in the research field has exploded and now includes chemists and engineers focused on developing new and better microchips, as well as biologists and biochemists who have begun to apply this exciting and still relatively new methodology to real-world problems. This chapter seeks to outline the historical development of microchip, the key elements of microchip capillary electrophoresis, and finally some of the important applications being developed that utilize microchip capillary electrophoresis.
微芯片毛细管电泳在20世纪90年代初出现，是一种用于高速分离生物化合物（包括DNA和蛋白质）的有趣且新颖的方法。自该领域早期发展以来，研究领域的发展呈爆发式增长，现在包括专注于开发新型更好微芯片的化学家和工程师，以及已开始将这种令人兴奋且仍相对较新的方法应用于实际问题的生物学家和生物化学家。本章旨在概述微芯片的历史发展、微芯片毛细管电泳的关键要素，以及最后一些正在开发的利用微芯片毛细管电泳的重要应用。
