Muehllehner Gerd, Karp Joel S
Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Phys Med Biol. 2006 Jul 7;51(13):R117-37. doi: 10.1088/0031-9155/51/13/R08. Epub 2006 Jun 20.
The developments in positron emission tomography (PET) are reviewed with an emphasis on instrumentation for clinical PET imaging. After a brief summary of positron imaging before the advent of computed tomography, various improvements are highlighted including the move from PET scanners with septa to fully 3D scanners, changes in the preferred scintillators, efforts to improve the energy discrimination, and improvements in attenuation correction. Time-of-flight PET imaging is given special attention due to the recent revival of this technique, which promises significant improvement. Besides technical instrumentation efforts, other factors which influenced the acceptance of clinical PET are also discussed.
本文综述了正电子发射断层扫描（PET）的发展，重点介绍了临床PET成像设备。在简要总结计算机断层扫描出现之前的正电子成像后，突出了各种改进，包括从带隔板的PET扫描仪向全3D扫描仪的转变、首选闪烁体的变化、提高能量分辨的努力以及衰减校正的改进。由于该技术最近的复兴有望带来显著改进，飞行时间PET成像受到了特别关注。除了技术设备方面的努力，还讨论了影响临床PET接受度的其他因素。
