Mineta Sho, Shimanuki Kimiyoshi, Sugiura Atsushi, Tsuchiya Yoshikazu, Kaneko Masahiro, Sugiyama Yoshihiko, Akimaru Koho, Tajiri Takashi
Department of Surgery, Aizu Central Hospital, Tokyo, Japan.
J Nippon Med Sch. 2006 Jun;73(3):169-74. doi: 10.1272/jnms.73.169.
Chronic anisakiasis of the colon is rare and difficult to diagnose. We report a case of chronic anisakiasis associated with advanced colonic carcinoma. A 69-year-old man was admitted for abdominal pain, diarrhea, and urticaria. Right hemicolectomy was performed because of an obstruction of the ascending colon and a palpable tumor of the right lower abdomen. The lesion was thought to be located in the deeper layers of the ascending colon. Preoperative examinations failed to detect the coexistence of anisakiasis and carcinoma of the colon. The anisakis was identified morphologically in the intestinal wall of the resected specimen and by an elevated titer of an IgE antibody specific to the parasite. Seventy-five cases of colonic and rectal anisakiasis, including the present case, have been reported in Japan. This is the only reported case of anisakiasis to appear in association with colonic carcinoma.
结肠慢性异尖线虫病罕见且难以诊断。我们报告一例与晚期结肠癌相关的慢性异尖线虫病病例。一名69岁男性因腹痛、腹泻和荨麻疹入院。由于升结肠梗阻及右下腹可触及肿物,行右半结肠切除术。病变被认为位于升结肠较深层。术前检查未能发现异尖线虫病与结肠癌并存。在切除标本的肠壁中通过形态学鉴定出异尖线虫,并通过针对该寄生虫的IgE抗体滴度升高得以确认。包括本病例在内,日本已报告75例结肠和直肠异尖线虫病病例。这是唯一一例报告的与结肠癌相关的异尖线虫病病例。