Cordeiro Joacir Graciolli, Prevedello Daniel Monte-Serrat, da Silva Ditzel Léo Fernando, Pereira Carlos Umberto, Araújo João Cândido
Department of Neurosurgery, Hospital Nossa Senhora das Graças, Curitiba, PR, and Federal University of Sergipe, Aracaju, SE, Brazil.
Arq Neuropsiquiatr. 2006 Jun;64(2A):300-2. doi: 10.1590/s0004-282x2006000200023. Epub 2006 Jun 9.
Cervical uterine cancer (CUC) spreads locally (pelvis and paraortic lymphnodes) or distantly (lungs, liver and bones). Metastasis to central nervous system (CNS) are rare. There are about 80 cases reported in the literature. Outcome is poor and survival varies from 3 to 6 months. Three cases of CNS metastasis from CUC are reported, one infratentorial and two supratentorials in location. In one patient, the initial manifestation was due to the cerebral lesion, a feature reported for the first time. All cases were treated by surgery, radiotherapy and/or chemotherapy. Clinical findings and treatment options of these rare lesions are reviewed.
宫颈子宫癌（CUC）可局部扩散（至盆腔和腹主动脉旁淋巴结）或远处转移（至肺、肝和骨）。转移至中枢神经系统（CNS）的情况较为罕见。文献中报道了约80例。预后较差，生存期从3个月至6个月不等。本文报道了3例CUC发生CNS转移的病例，其中1例位于幕下，2例位于幕上。在1例患者中，首发表现是由脑部病变引起的，这是首次报道的特征。所有病例均接受了手术、放疗和/或化疗。本文对这些罕见病变的临床发现和治疗选择进行了综述。
