Caselli Graziella, Pozzi Lucia, Vaupel James W, Deiana Luca, Pes Gianni, Carru Ciriaco, Franceschi Claudio, Baggio Giovannella
University of Rome, La Sapienza, Department of Demography, Italy.
Exp Gerontol. 2006 Aug;41(8):727-36. doi: 10.1016/j.exger.2006.05.009. Epub 2006 Jun 21.
This paper aims to discuss the validation and family determinants affecting the longevity of Sardinian centenarians, using a genealogical approach. This preliminary study presents the first results of a genealogical tree reconstruction of selected centenarians aged 105 and over, from certain areas. These are mostly situated in the province of Nuoro, an area with the highest rate of centenarians and where the female-to-male sex ratio tends to be male-biased. An accurate centenarian age validation was performed that required a meticulous examination of numerous civil status records and parish registers. An important finding was that longevity occurs among the ascendants of a particular branch of the family. The data used are still provisional but, should it apply to other validated cases, it would provide empirical evidence of a genetic component in longevity. A more thorough examination of the data available may yield deeper insights into the role played by endogamy and consanguinity.
本文旨在采用系谱学方法，探讨影响撒丁岛百岁老人长寿的验证情况及家庭因素。这项初步研究呈现了对特定地区105岁及以上选定百岁老人进行系谱树重建的首批结果。这些地区大多位于努奥罗省，该地区百岁老人比例最高，且男女比例倾向于男性偏高。对百岁老人的年龄进行了准确验证，这需要仔细查阅众多民事身份记录和教区登记簿。一个重要发现是，长寿出现在家族特定分支的先辈中。所使用的数据仍是临时的，但如果适用于其他经过验证的案例，将为长寿中的遗传成分提供实证依据。对现有数据进行更深入的研究可能会更深入地了解近亲通婚和血缘关系所起的作用。
