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Drugs for anovulatory infertility in polycystic ovary syndrome.

作者信息

Al-Inany Hesham, Johnson Neil

出版信息

BMJ. 2006 Jun 24;332(7556):1461-2. doi: 10.1136/bmj.332.7556.1461.

DOI:10.1136/bmj.332.7556.1461
PMID:16793784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1482323/
Abstract
摘要

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Drugs for anovulatory infertility in polycystic ovary syndrome.用于多囊卵巢综合征无排卵性不孕症的药物。
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2
What is the best first-step therapeutic approach in treating anovulatory infertility in patients with polycystic ovary syndrome? Questions that are still unanswered.治疗多囊卵巢综合征患者无排卵性不孕症的最佳第一步治疗方法是什么？问题仍未得到解答。
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Comparison of metformin and clomiphene citrate therapy for induction of ovulation in the polycystic ovary syndrome.比较二甲双胍和枸橼酸氯米酚治疗多囊卵巢综合征诱导排卵的疗效。
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Evaluation and treatment of anovulatory and unexplained infertility.排卵障碍性和不明原因不孕的评估与治疗。
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Metformin: an advance in ovulation induction.二甲双胍：诱导排卵方面的一项进展。
Ir Med J. 2005 May;98(5):133-4.
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Metformin is a reasonable first-line treatment option for non-obese women with infertility related to anovulatory polycystic ovary syndrome--a meta-analysis of randomised trials.二甲双胍是无排卵性多囊卵巢综合征相关不孕症非肥胖女性合理的一线治疗选择——一项随机试验的荟萃分析
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7
Laparoscopic ovarian diathermy vs clomiphene citrate plus metformin as second-line strategy for infertile anovulatory patients with polycystic ovary syndrome: a randomized controlled trial.腹腔镜卵巢电灼术与枸橼酸氯米酚加二甲双胍作为多囊卵巢综合征排卵障碍患者二线治疗策略的比较：一项随机对照试验。
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Clomiphene citrate versus metformin as first-line approach for the treatment of anovulation in infertile patients with polycystic ovary syndrome.枸橼酸氯米芬与二甲双胍作为多囊卵巢综合征不孕患者无排卵治疗的一线方法比较
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PCOSMIC: a multi-centre randomized trial in women with PolyCystic Ovary Syndrome evaluating Metformin for Infertility with Clomiphene.PCOSMIC 研究：多囊卵巢综合征不孕患者中二甲双胍对比氯米酚的多中心随机临床试验
Hum Reprod. 2010 Jul;25(7):1675-83. doi: 10.1093/humrep/deq100. Epub 2010 Apr 30.
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Metformin use in women with polycystic ovary syndrome.多囊卵巢综合征妇女中二甲双胍的应用。
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本文引用的文献

1
Effect of clomifene citrate plus metformin and clomifene citrate plus placebo on induction of ovulation in women with newly diagnosed polycystic ovary syndrome: randomised double blind clinical trial.枸橼酸氯米芬联合二甲双胍与枸橼酸氯米芬联合安慰剂对新诊断多囊卵巢综合征女性诱导排卵的影响：随机双盲临床试验
BMJ. 2006 Jun 24;332(7556):1485. doi: 10.1136/bmj.38867.631551.55. Epub 2006 Jun 12.
2
No more surrogate end-points in randomised trials: the PCOSMIC trial protocol for women with polycystic ovary syndrome using metformin for infertility with clomiphene.随机试验中不再使用替代终点：多囊卵巢综合征女性使用二甲双胍联合克罗米芬治疗不孕症的PCOSMIC试验方案
Aust N Z J Obstet Gynaecol. 2006 Apr;46(2):141-5. doi: 10.1111/j.1479-828X.2006.00544.x.
3
Obesity, polycystic ovary syndrome, infertility treatment: asking obese women to lose weight before treatment increases stigmatisation.肥胖、多囊卵巢综合征、不孕治疗：要求肥胖女性在治疗前减肥会增加污名化。
BMJ. 2006 Mar 11;332(7541):609. doi: 10.1136/bmj.332.7541.609-b.
4
Should obese women with polycystic ovary syndrome receive treatment for infertility?患有多囊卵巢综合征的肥胖女性应该接受不孕症治疗吗？
BMJ. 2006 Feb 25;332(7539):434-5. doi: 10.1136/bmj.332.7539.434.
5
Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome.一项前瞻性平行随机、双盲、双模拟对照临床试验，比较枸橼酸氯米芬和二甲双胍作为非肥胖型多囊卵巢综合征无排卵女性促排卵一线治疗药物的疗效。
J Clin Endocrinol Metab. 2005 Jul;90(7):4068-74. doi: 10.1210/jc.2005-0110. Epub 2005 Apr 19.
6
Metformin in polycystic ovary syndrome.
Curr Opin Obstet Gynecol. 2004 Dec;16(6):481-6. doi: 10.1097/00001703-200412000-00008.
7
Insulin-sensitizing agents as primary therapy for patients with polycystic ovarian syndrome.胰岛素增敏剂作为多囊卵巢综合征患者的一线治疗方法。
Hum Reprod. 2004 Nov;19(11):2474-83. doi: 10.1093/humrep/deh440. Epub 2004 Sep 9.
8
Metformin in polycystic ovary syndrome: systematic review and meta-analysis.二甲双胍治疗多囊卵巢综合征：系统评价与荟萃分析。
BMJ. 2003 Oct 25;327(7421):951-3. doi: 10.1136/bmj.327.7421.951.
9
Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome.用于多囊卵巢综合征的胰岛素增敏药物（二甲双胍、曲格列酮、罗格列酮、吡格列酮、D-手性肌醇）
Cochrane Database Syst Rev. 2003(3):CD003053. doi: 10.1002/14651858.CD003053.