Griffiths R
Department of Zoology, University of Oxford, U.K.
Proc Biol Sci. 1991 May 22;244(1310):123-8. doi: 10.1098/rspb.1991.0060.
The sex-determining region gene (SRY) is a recently discovered candidate for the mammalian testis determining factor (TDF). The gene appears to form part of a family with several autosomal representatives. I have investigated the occurrence of SRY-related sequences in birds. The polymerase chain reaction was used to isolate six homologues of the conserved motif of the SRY gene from the lesser black-backed gull (Larus fuscus). Female unique copies of the motif are apparently absent. Sequence similarity and phylogenetic parsimony methods suggest that, irrespective of avian or mammalian origin, SRY-type sequences fall into two subfamilies. This is consistent with the presence of two archetypal genes in an ancestor common to both taxonomic classes.
性别决定区基因（SRY）是最近发现的哺乳动物睾丸决定因子（TDF）的候选基因。该基因似乎是一个家族的一部分，有几个常染色体代表成员。我研究了鸟类中与SRY相关序列的存在情况。利用聚合酶链反应从小型黑背鸥（Larus fuscus）中分离出了SRY基因保守基序的六个同源物。显然不存在该基序的雌性特异拷贝。序列相似性和系统发育简约法表明，无论起源于鸟类还是哺乳动物，SRY型序列都可分为两个亚家族。这与两个分类类群共同祖先中存在两个原型基因是一致的。
