Kim Seon Mee, Han Jee Hye, Park Hye Soon
Department of Family Medicine, College of Medicine, Korea University, Seoul, Korea.
Circ J. 2006 Jul;70(7):820-6. doi: 10.1253/circj.70.820.
Low levels of high-density lipoprotein cholesterol (HDL-C), as well as high levels of low-densi-ty lipoprotein cholesterol, play a crucial role in the development of cardiovascular disease, which has shown a remarkable increase in Korea.
Data were obtained from the 1998 Korean National Health and Nutrition Examination Survey, which was a cross-sectional national health survey. The total study population amounted to 7,300 individuals (3,283 men, 4,617 women), aged 18 years and older. The prevalence of low HDL-C levels, as proposed by National Cholesterol Education Program Adult Treatment Panel III or International Diabetes Federation, was 23.8% in men and 47.5% in women. After adjusting for independent variables, there was a greater risk of low HDL-C with an increased body mass index, abdominal obesity, cigarette smoking, and decreased alcohol consumption. Physically inactive lifestyle in men and low fat intake in women were identified as factors associated with low HDL-C level.
The prevalence of low HDL-C levels is relatively high among Koreans, which may have important implications for public health. Identified associated factors should be considered for reducing the risk of low HDL-C levels in Koreans.
高密度脂蛋白胆固醇（HDL-C）水平低以及低密度脂蛋白胆固醇水平高在心血管疾病的发生发展中起着关键作用，在韩国心血管疾病的发病率已显著上升。
数据来自1998年韩国全国健康与营养检查调查，这是一项全国性横断面健康调查。研究总人群为7300名18岁及以上的个体（男性3283名，女性4617名）。根据美国国家胆固醇教育计划成人治疗小组第三次报告或国际糖尿病联盟提出的标准，低HDL-C水平的患病率在男性中为23.8%，在女性中为47.5%。在对自变量进行调整后，体重指数增加、腹部肥胖、吸烟以及饮酒量减少会增加低HDL-C的风险。男性缺乏体育活动的生活方式和女性低脂肪摄入被确定为与低HDL-C水平相关的因素。
韩国人低HDL-C水平的患病率相对较高，这可能对公众健康具有重要意义。为降低韩国人低HDL-C水平的风险，应考虑已确定的相关因素。
