Division of Cardiovascular Diseases, Center for Biomedical Sciences, National Institute of Health, Seoul 122-701, South Korea.
Int J Cardiol. 2010 Mar 18;139(3):234-40. doi: 10.1016/j.ijcard.2008.10.011. Epub 2008 Nov 14.
It is widely recognized that dietary factors play important roles in the development of cardiovascular disease (CVD). We evaluated the association between carbohydrate intake and CVD risk factors, using data from the third Korea National Health and Nutrition Examination Survey (KNHANES III).
A nationally representative sample of Korean adults (1536 men, 2235 women), aged 20 to 69 years, was divided into three groups according to carbohydrate intake (% of energy), based on the Dietary Reference Intakes (DRI, 55-70% of energy) for Koreans. Then, we examined whether excessive carbohydrate intake was related to CVD risk factors.
Mean carbohydrate intake (% of energy) was 72.8% (321 g/day), above the DRI for Korean adults (55-70%). A high carbohydrate intake (>70% of energy) was associated with higher BMI, blood pressure, fasting glucose, triglycerides, and LDL-cholesterol levels in women. After adjusting for covariates, such as age, energy intake, alcohol consumption, smoking status, and physical activity, high carbohydrate intakes (>70% of energy) were significantly associated with diabetes mellitus and low HDL-cholesterol (HDL-C) in women. In men, however, only total cholesterol was inversely associated with high carbohydrate intake.
Higher carbohydrate intakes than the DRI for Koreans were significantly associated with diabetes mellitus and low HDL-C levels in women. These results suggest that improvement of dietary patterns may be an important approach to the prevention of CVD in Korean women.
人们普遍认为,饮食因素在心血管疾病(CVD)的发展中起着重要作用。我们利用第三次韩国国家健康和营养检查调查(KNHANES III)的数据,评估了碳水化合物摄入量与 CVD 危险因素之间的关系。
将年龄在 20 至 69 岁的韩国成年人(男性 1536 人,女性 2235 人)分为三组,根据碳水化合物摄入量(占能量的百分比),基于韩国人的膳食参考摄入量(DRI,占能量的 55-70%)。然后,我们检查了过量的碳水化合物摄入是否与 CVD 危险因素有关。
平均碳水化合物摄入量(占能量的百分比)为 72.8%(321 克/天),高于韩国成年人的 DRI(55-70%)。高碳水化合物摄入(>70%的能量)与女性的 BMI、血压、空腹血糖、甘油三酯和 LDL-胆固醇水平升高有关。在调整了年龄、能量摄入、饮酒、吸烟状况和体力活动等混杂因素后,高碳水化合物摄入(>70%的能量)与女性的糖尿病和低 HDL-胆固醇(HDL-C)显著相关。然而,在男性中,只有总胆固醇与高碳水化合物摄入呈负相关。
高于韩国 DRI 的碳水化合物摄入量与女性的糖尿病和低 HDL-C 水平显著相关。这些结果表明,改善饮食模式可能是预防韩国女性 CVD 的重要方法。