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微流控流动聚焦装置的模拟

Simulation of a microfluidic flow-focusing device.

作者信息

Dupin Michael M, Halliday Ian, Care Chris M

机构信息

Steele Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 May;73(5 Pt 2):055701. doi: 10.1103/PhysRevE.73.055701. Epub 2006 May 17.

DOI:10.1103/PhysRevE.73.055701
PMID:16802991
Abstract

We present a model of microfluidic flow of several completely immiscible fluids and use it to simulate a whole flow focusing device chamber. Our efficient, practical model supports a large parameter space, spanned by surface wetting, surface tension, liquid-liquid wetting, viscosity ratio, and inlet velocity. It is based upon an N-component lattice Boltzmann method with interrupted coalescence [Dupin, Philos. Trans. R. Soc. London, Ser. A 362, 1885 (2004)], here adapted for calculations at low capillary and Reynolds numbers, with wetting and significantly reduced spurious flow. Results over 2 orders of magnitude in Reynolds number are presented.

摘要

我们提出了一种用于几种完全不混溶流体的微流体流动模型,并使用该模型模拟了整个流动聚焦装置腔室。我们高效、实用的模型支持一个由表面润湿性、表面张力、液 - 液润湿性、粘度比和入口速度所跨越的大参数空间。它基于具有间断聚并的N组分格子玻尔兹曼方法[迪潘,《伦敦皇家学会哲学学报》,A辑362, 1885 (2004)],此处适用于低毛细管数和雷诺数下的计算,具有润湿性且显著减少了虚假流动。给出了雷诺数超过两个数量级的结果。

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