Nagarsheth N P, Harrison M, Kalir T, Rahaman J
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai School of Medicine, 1176 Fifth Avenue, New York, NY 10029, USA.
Int J Gynecol Cancer. 2006 May-Jun;16(3):1458-61. doi: 10.1111/j.1525-1438.2006.00584.x.
Malignant pericardial effusion with cardiac tamponade is a rare manifestation of metastatic gynecological cancer. A 35-year-old female was diagnosed with clear cell adenocarcinoma of the vagina. Four years after partial vaginectomy, she developed regional recurrence and was treated with surgical excision followed by platinum-based chemotherapy and radiation therapy. Six years later, the patient was diagnosed with lung metastases and received a combination adriamycin and platinum-based chemotherapy. Shortly after completing treatment, she presented with weakness and was found to be hypotensive on physical exam. Computed tomography scan confirmed a pericardial effusion with evidence of bilateral heart failure. She underwent an emergent pericardiocentesis and eventual pericardial window procedure. Metastatic adenocarcinoma of the vagina can present with malignant pericardial effusion with cardiac tamponade. Therefore, gynecologists and gynecological oncologists need to be familiar with the diagnosis and management of this disease process.
恶性心包积液伴心脏压塞是转移性妇科癌症的一种罕见表现。一名35岁女性被诊断为阴道透明细胞腺癌。部分阴道切除术后四年，她出现局部复发，接受了手术切除，随后进行铂类化疗和放射治疗。六年后，患者被诊断为肺转移，并接受了阿霉素联合铂类化疗。完成治疗后不久，她出现乏力，体格检查发现血压降低。计算机断层扫描证实有心包积液及双侧心力衰竭的证据。她接受了紧急心包穿刺术及最终的心包开窗手术。阴道转移性腺癌可表现为恶性心包积液伴心脏压塞。因此，妇科医生和妇科肿瘤学家需要熟悉这一疾病过程的诊断和管理。
